Dec 11, 2025
In this episode Dr. Gillian Beauchamp sits down with Dr. Robert “Cole” Pueringer to discuss 3 key features of fentanyl which lead to high opioid tolerance. This high opioid tolerance can lead to more severe withdrawal syndromes and difficulty with initiating buprenorphine or methadone. Rapid inpatient methadone initiation may be more effective than outpatient initiation.